Characterization of a Systems Biology Platform Incorporating Human Microglia with Rodent Neurons & Astrocytes
Time: 2:15 pm
day: Day One
Details:
- Outlining development of chimeric culture system where hiPSC microglia robustly respond to inflammatory stimuli
- Demonstrating functional and morphological effects of microglia-dependent inflammation using cytokine release, neuronal function and high content imaging assays
- Platform that recapitulates neuroinflammation systems biology amenable for neuroinflammatory compound screening
