Ralph Minter

Chief Scientific Officer Alchemab Therapeutics

Ralph Minter is Chief Scientific Officer at Alchemab Therapeutics and leads the antibody discovery efforts, in Neuroscience and other areas. Prior to joining Alchemab, Ralph was Senior Director in Antibody Discovery and Protein Engineering at AstraZeneca where he led discovery teams and developed candidate drugs across multiple disease areas. Before joining AstraZeneca, he was part of Cambridge Antibody Technology (CAT), which later became MedImmune. In addition to antibody discovery, Ralph has worked extensively on phenotypic, or target-agnostic, antibody screening which has yielded many novel therapeutic targets, some of which are now being tested in clinical trials. Ralph earned his PhD in Immunology from Durham University and a BSc in Pathology and Microbiology from Bristol University.

Seminars

Wednesday 15th April 2026
Releasing the Microglial Brake: CD33 Modulation as a New Route to Restore Protective Immunity in Alzheimer’s Disease
12:10 pm
  • Unlock a previously underexploited microglial pathway to help restore homeostatic, disease-resolving activity without relying solely on TREM2-centric strategies
  • Enables a more direct and tractable mechanism for restoring microglial phagocytosis and immune balance, supporting clearer translation from biology to therapeutic design
  • Strengthen the foundation for precision microglial therapeutics by broadening the set of actionable immune checkpoints that shape microglial behaviour across disease stages
Ralph Minter