Ioannis-Alexandros Gampierakis
Postdoctoral Research Fellow, Inflammation & Immunology Pfizer
Ioannis Gampierakis, Ph.D. is an industry Research Fellow whose work bridges neuroimmunology, epithelial biology, and gut-brain communication. His PhD research uncovered how experimental colitis disrupts adult hippocampal neurogenesis and microglia function, proposing a mechanistic link between intestinal inflammation and altered brain function. At Harvard University, he contributed to defining pathways involved in vascular rejuvenation during brain aging, including identifying peripheral factors capable of reversing age-associated endothelial decline. At Pfizer, he leads research investigating rare epithelial cells in the human colon and their role in metabolic and inflammatory states. His work integrates mechanistic discovery with translational relevance across inflammation, metabolism, and neurodegeneration.
Seminars
- Discussions into the gut-brain-immune axis as a critical pathway where environmental insults and microbiome imbalances initiate peripheral immune responses that propagate inflammation to the brain
- Explore how microbiome imbalances and peripheral immune activation amplify gut-brain signalling and contribute to chronic neuroinflammation
- Discuss opportunities to leverage gut-brain axis research for biomarker discovery and precision strategies to prevent or slow neurodegenerative disease progression
