Bilal Cakir
Associate Principal Scientist Merck
Seminars
Wednesday 15th April 2026
Innovating Organoid Technologies to Recapitulate Complex CNS Immune Cell Interactions & Bolster Neuroinflammatory Target Discovery
1:40 pm
- How organoid models are used to simulate the BBB and enable small molecule screening for CNS drug candidates
- Addressing challenges in organoid maturity, reproducibility, and relevance to human disease biology
- The importance of incorporating multiple CNS cell types, including microglia and astrocytes, for inflammation studies
- Comparing organoid approaches with traditional animal and cell-based models in neuroinflammation research
- Emerging efforts to harmonize organoid protocols and enhance translatability to clinical settings
