Kate Monroe

Kate Monroe

Company: Denali Therapeutics

Job title: Associate Director and Senior Scientist

Seminars:

Mechanisms of Targeting TREM2 with a Dual Function Antibody 11:15 am

Microglia lipid accumulation is a hallmark of TREM2 lof in vivo upon chronic myelin challenge The R47H AD risk allele recapitulates lipid metabolism defects in human iPSCderived microglia A TREM2 antibody reduces microglia lipid accumulation in vitro while reducing Abeta plaque levels in an AD mouse modelRead more

day: Day Two

Mechanisms of Targeting TREM2 with a Dual Function Antibody 11:15 am

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