April 17-18, 2019
Boston, USA





Workshop A
Tuesday, April 16

08.30 - 11.30
Basic Neuroimmunology Course: Protection & Pathology
Workshop Leader: Marco Colonna, Professor, Washington University

Review the basic neuroimmunology of the brain to understand the different peripheral and central immune cells, their interactions and how they contribute to brain function or disease pathology.
This session will cover the innate immune pathways in neurodegeneration.

Join this workshop to:

  • Improve your understanding of the different cells involved in the innate immune responses in the brain
  • Understand how they are affected in neurodegeneration
  • Explore different approaches for determining microglial function/dysfunction

Marco Colonna, Professor, Washington University

Dr. Marco Colonna was born in Parma, Italy, received his medical degree at Parma University and completed his postdoctoral training at Harvard Medical School (Cambridge, Massachusetts, USA). He became a scientific member of the Basel Institute for Immunology in Basel, Switzerland. Since 2001 he has been a Professor of Pathology & Immunology at Washington University School of Medicine in St. Louis, MO. Dr. Colonna’s research focuses on immunoreceptors. In this field his accomplishments encompass identification and characterization of the Killer cell Ig-like receptors and HLA-C polymorphisms as their inhibitory ligands, as well as the discovery of the LILR and TREM inhibitory and activating receptor families. Through analysis of the cellular distribution of these receptors, he identified plasmacytoid dendritic cells as source of IFN-a/b in anti-viral responses and innate lymphoid cells that produce IL-22 in mucosae. His current areas of research include: 1) Innate lymphoid cells in mucosal immunity. 2) Plasmacytoid dendritic cells in host defense and autoimmunity.
3) Innate immunoreceptors in Alzheimer’s disease.v

Workshop B
Tuesday, April 18

12.00 - 15.00
Identifying Translational Phenotypes to Improve Clinical Efficacy
Workshop Leader: Charlotte Madore, Research Fellow, Harvard Medical School

A focused session on neuroinflammatory phenotypes to screen around and understanding the translation of both phenotypes from in vitro work to in vivo work. In this workshop, we will cover microglia modulation of functional properties during processes of tissue injury, neuroinflammation and neurodegeneration.

Attend this session to:

  • Improve your understanding on microglia cell phenotypes and gene signatures
  • Learn how to improve translation from in vitro to in vivo work
  • Explore different approaches for in vitro and mouse models

Charlotte Madore, Research Fellow, Harvard Medical School