Pre-Conference Workshop Day

Workshop A: Targeting Inflammasome-Mediated Inflammatory Pathways in Neurodegenerative Diseases

Wednesday August 5 | 9:00am-12:00pm

Neuroinflammation and neurodegeneration are associated with abnormal deposition of aggregated host proteins, such as amyloid, α-synuclein, and prions, which can activate inflammasomes. Their activation induces an innate immune response involving the prominent innate immune cells in the brain for inflammasome activation, microglia. Additional CNS-resident cell types including astrocytes and neurons, as well as infiltrating myeloid cells from the periphery, also express and activate inflammasomes.

Attend this workshop to:

  • Discuss current understanding of the role of inflammasomes in common neurodegenerative diseases of the brain
  • Highlight inflammasome-targeted strategies that may potentially treat these diseases
  • Review the current efforts to target the inflammasome for neurodegenerative diseases
Matt Havrda - Dartmouth

Matthew Havrda
Assistant Professor
The Geisel School of Medicine at Dartmouth


Katherine Von Herrmann
Guarini School of Graduate and Advanced Studies at Dartmouth